Mechanobiology and Signalling
We are interested in studying the mechanosensing and signalling mechanisms of stem cells in physiologically relevant matrices. Particularly, we study cell-matrix interactions, cell-cell interactions, and cytoskeletal responses of cells under active mechanical loading and in microenvironments with tunable mechanical stiffnesses. For example, using bioreactor technologies with different loading modes, we can study the behavior of stem cells encapsulated in collagen microspheres.