The research group of Microfluidics and Soft Matter.


The research group

There are multiple research sub-groups. We currently have post-doctoral fellows, research postgraduate students, research assistants, and interns from diverse countries worldwide.



The research group is housed in Haking Wong Building on the main campus.



Publication Highlights

"Tuning Material States and Functionalities of G-Quadruplex-Modulated RNA-Peptide Condensates"
  • by Wei Guo, Danyang Ji, Andrew B Kinghorn, Feipeng Chen, Yi Pan, Xiufeng Li, Qingchuan Li, Wilhelm TS Huck, Chun Kit Kwok* and Ho Cheung Shum*, Journal of the American Chemical Society, 145(4), 2375-2385 (2023)

"Synthetic Membraneless Droplets for Synaptic-Like Clustering of Lipid Vesicles"
  • by Qingchuan Li*, Qingchun Song, Wei Guo, Yang Cao, Xinyu Cui, Dairong Chen* and Ho Cheung Shum*, Angewandte Chemie International Edition, 135(45), e202313096 (2023)

"Vascular network-inspired fluidic system (VasFluidics) with spatially functionalizable membranous walls"
  • by Yafeng Yu, Yi Pan, Yanting Shen, Jingxuan Tian, Ruotong Zhang, Wei Guo, Chang Li and Ho Cheung Shum*, Nature Communications, 15(1), 1437 (2024)

"Plant-inspired TransfOrigami microfluidics"
  • by Yi Pan, Zhenyu Yang, Chang Li, Sammer Ul Hassan and Ho Cheung Shum*, Science Advances, 8(18), eabo1719 (2022)

"High-throughput screening of genetic and cellular drivers of syncytium formation induced by the spike protein of SARS-CoV-2"
  • by Charles W. F. Chan, Bei Wang, Lang Nan, Xiner Huang, Tianjiao Mao, Hoi Yee Chu, Cuiting Luo, Hin Chu*, Gigi C. G. Choi*, Ho Cheung Shum* and Alan S. L. Wong*, Nature Biomedical Engineering, 1(1), 1-19 (2023)

"Generation of Fermat’s spiral patterns by solutal Marangoni-driven coiling in an aqueous two-phase system"
  • by Yang Xiao, Neil M Ribe*, Yage Zhang, Yi Pan, Yang Cao and Ho Cheung Shum*, Nature Communications, 13(1), 7206 (2022)

"Heterogeneous Self-Assembly of a Single Type of Nanoparticle Modulated by Skin Formation"
  • by Chang Li, Yafeng Yu, Huizeng Li*, Haisong Lin, Huanqing Cui, Yi Pan, Ruotong Zhang, Yanlin Song* and Ho Cheung Shum*, ACS Nano, 17(12), 11645-11654 (2023)

"Rapid Multi-Level Compartmentalization of Stable All-Aqueous Blastosomes by Interfacial Aqueous Phase Separation"
  • by Shipei Zhu, Joe Forth, Ganhua Xie, Youchuang Chao, Jingxuan Tian, Thomas P. Russell* and Ho Cheung Shum*, ACS Nano, 14(9), 11215-11224 (2020)

  • by Shipei Zhu, Ganhua Xie, Huanqing Cui, Qingchuan Li, Joe Forth, Shuai Yuan, Jingxuan Tian, Yi Pan, Wei Guo, Yu Chai, Yage Zhang, Zhenyu Yang, Ryan Wing Hei Yu, Yafeng Yu, Sihan Liu, Youchuang Chao, Yinan Shen, Sai Zhao, Thomas P Russell* and Ho Cheung Shum*, ACS Nano, 16(9), 13761-13770 (2022)

"Fibro-Gel: An All-Aqueous Hydrogel Consisting of Microfibers with Tunable Release Profile and its Application in Wound Healing"
  • by Yanting Shen, Yuan Liu, Janine K Nunes, Chenmin Wang, Miao Xu, Michael KT To*, Howard A Stone* and Ho Cheung Shum*, Advanced Materials, 35(19), 2211637 (2023)

"Pixelating Responsive Structural Color via a Bioinspired Morphable Concavity Array (MoCA) Composed of 2D Photonic Crystal Elastomer Actuators"
  • by Yi Pan, Chang Li, Xiaoyu Hou, Zhenyu Yang, Mingzhu Li* and Ho Cheung Shum*, Advanced Science, 10, 2300347 (2023)

"Dynamic Assembly of Viscoelastic Networks by Aqueous Liquid–Liquid Phase Separation and Liquid–Solid Phase Separation (AqLL-LS PS2)"
  • by Huanqing Cui, Yage Zhang, Yinan Shen, Shipei Zhu, Jingxuan Tian, Qingchuan Li, Yi Shen, Sihan Liu, Yang Cao and Ho Cheung Shum*, Advanced Materials, 2205649 (2022)

"One-Pot Self-Assembly of Dual-Color Domes Using Mono-Sized Silica Nanoparticles"
  • by Chang Li, Yafeng Yu, Huizeng Li*, Jingxuan Tian, Wei Guo, Yanting Shen, Huanqing Cui, Yi Pan, Yanlin Song* and Ho Cheung Shum*, Nano Letters, 22(13), 5236-5243 (2022)

"Non-associative phase separation in an evaporating droplet as a model for prebiotic compartmentalization"
  • by Wei Guo, Andrew Kinghorn, Yage Zhang, Qingchuan Li, Aditi Poonam, Julian Tanner* and Ho Cheung Shum*, Nature Communications, 12, 3194 (2021)

"Dynamic regimes of electrified liquid filaments"
  • by Tiantian Kong*, Howard A. Stone*, Liqiu Wang and Ho Cheung Shum*, Proceedings of the National Academy of Sciences, 115(24), 6159-6164 (2018)

"Development and future of droplet microfluidics" by Lang Nan, Huidan Zhang, David A Weitz and Ho Cheung Shum*, Lab on a Chip, 24, 1210 (2024)


Open Positions

  • MSc in Mechanical Engineering
  • MPhil
  • PhD
  • Post-Doc

Contact Us

Prof. Anderson Shum

  • Email: ashum@hku.hk
  • Phone: (852) 3917 7904
  • Office: Room 7-25, 7/F, Haking Wong Building, The University of Hong Kong, Pokfulam Road, Pokfulam, Hong Kong